GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UCEC | cis | rs10935120 | 1 | rs9827987 | chr3:134272621 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.65 | 7.29E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9828398 | chr3:41895893 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.25 | 3.94E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9828815 | chr3:134265749 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9830064 | chr3:41881801 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.33 | 2.61E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9830469 | chr3:41762535 | ULK4 | chr3:41288091-42003660:- | 0.52 | 6.44 | 1.51E-9 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9832785 | chr3:134213070 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.65 | 7.03E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9834098 | chr3:41833493 | ULK4 | chr3:41288091-42003660:- | 0.51 | 5.97 | 1.63E-8 | Diastolic blood pressure |
| UCEC | cis | rs10935120 | 1 | rs9834755 | chr3:134206845 | ANAPC13 | chr3:134196547-134204865:- | 0.39 | 4.48 | 1.43E-5 | Height |
| UCEC | cis | rs10935120 | 1 | rs9835204 | chr3:134261342 | ANAPC13 | chr3:134196547-134204865:- | 0.4 | 4.62 | 8.08E-6 | Height |
| UCEC | cis | rs9815354 | 1 | rs9838965 | chr3:41927938 | ULK4 | chr3:41288091-42003660:- | -0.52 | -6.41 | 1.75E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9839399 | chr3:41928044 | ULK4 | chr3:41288091-42003660:- | -0.52 | -6.41 | 1.75E-9 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9840037 | chr3:41827522 | ULK4 | chr3:41288091-42003660:- | 0.51 | 5.91 | 2.21E-8 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9840532 | chr3:41885697 | ULK4 | chr3:41288091-42003660:- | 0.5 | 6.03 | 1.17E-8 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9842261 | chr3:41822708 | ULK4 | chr3:41288091-42003660:- | -0.48 | -5.21 | 6.19E-7 | Diastolic blood pressure |
| UCEC | cis | rs9815354 | 1 | rs9842305 | chr3:41998412 | ULK4 | chr3:41288091-42003660:- | -0.51 | -6.12 | 7.79E-9 | Diastolic blood pressure |